Clinical disease activity in autoimmune rheumatic patients receiving COVID-19 vaccines
Our research on the COURAGE cohort of our Heritage Study has been published in BMC Rheumatology! The COvid-19 vaccine immUne Response in Autoimmune rheumatic patients: a Ghanaian Experience (COURAGE) study, led by Dr. Ida Dzifa Dey, followed 38 patients with Systemic lupus erythematous (SLE) and Rheumatoid arthritis (RA) over 12 months at Korle-Bu Teaching Hospital, to access changes in clinical disease activity following COVID-19 vaccination, and to understand vaccine immune response in this subset.
Radiologic patterns of distant organ metastasis in advanced breast cancer patients
Breast cancer (BC) metastases to the abdomen and pelvis affect the liver, mesentery, retroperitoneum, peritoneum, bladder, kidney, ovary, and uterus. The study documented the radiological pattern and features of the chest, bone, abdominal and pelvic (AP) metastases among advanced breast cancer patients.
BRECXOME – Whole Exome Sequencing of Breast Cancer Tumour Samples from Ghanaian Women
Yemaachi shared findings from a its BreCXome study in an abstract presentation at the 14th AORTIC International Conference on Cancer in Africa
Assessing the utility of liquid biopsy for detecting actionable genetic mutations among indigenous Ghanaian women with metastatic breast cancer.
Liquid biopsy detected multiple actionable variants in Ghanaian women with breast cancer that a tissue-only workflow missed. cfDNA analysis featured less variations in sample preparation which is a key consideration in resource-limited settings.
Probing SARS-CoV-2-positive plasma to identify potential factors correlating with mild COVID-19 in Ghana, West Africa
West Africa has recorded a relatively higher proportion of asymptomatic coronavirus disease 2019 (COVID-19) cases than the rest of the world, and West Africa-specific host factors could play a role in this discrepancy. Here, [the authors] assessed the association between COVID-19 severity among Ghanaians with their immune profiles and ABO blood groups.
Unseen and unheard: African children with cancer are consistently excluded from clinical trials
Dr. Ella Amoako, Desmond Jumbam and Dr. Yaw Bediako authored an editorial in the January 2021 edition of BMJ Global Health, discussing the impact that excluding African participants from clinical trials has on childhood cancer research.