Precision Medicine on a Budget in Africa: using existing genetic data to mitigate adverse drug reactions to conventional cancer drugs.
Alexandra Lindsey Djomkam Zune , Charles Ochieng’ Olwal, Emmanuel Agbeli , Abdoulaye Baniré Diallo , Emmanuella Amoako, Yaw Bediako , Lily Paemka. Abstract Variations in drug-metabolizing enzymes and transporters are associated with adverse drug reactions (ADRs). ADRs to cancer drugs can differ among populations owing to environmental and genetic differences. Due to limited resources and prohibitive costs associated with drug development, African countries rely on […]