Yemaachi and Institut Pasteur Tunis Forge Oncogenetics Partnership to Sequence and Characterise Inflammatory Breast Cancer in Patients of African Descent
Partnership is emblematic of a global effort to characterise cancer development and progression in individuals of African descent, who have traditionally been excluded from genomic oncology studies and clinical trials 22nd October 2024, Tunis, Tunisia — Precision oncology company Yemaachi Biotech and Institut Pasteur Tunis today announced a research partnership investigating genomics in inflammatory breast […]
Chronogram: an R package for data curation and analysis of infection and vaccination cohort studies
David Greenwood, Marianne Shawe-Taylor, Hermaleigh Townsley, Joshua Gahir, Nikita Sahadeo, Yakubu Alhassan, Charlotte Chaloner, Oliver Galgut, Gavin Kelly, David L V Bauer, Emma C Wall, Mary Y Wu, Edward J Carr Bioinformatics Advances, Volume 4, Issue 1, 2024, vbae146, https://doi.org/10.1093/bioadv/vbae146 Abstract Motivation: Observational cohort studies that track vaccine and infection responses offer real-world data to inform pandemic policy. Translating biological hypotheses, such as whether different patterns of […]
Targeted gene panel sequencing of liquid and tissue biopsies reveals actionable genomic alterations in Ghanaian metastatic breast cancer cases
Emmanuella Amoako abc, Setor Amuzu a, Emmanuel Owusu Ofori b, Harry Sefoga Akligoh a, Randy Tackie a, Barikisu Anna Ibrahim a, Emmanuel Kofi Quaye a, Patrick Kafui Akakpo bcd, Luke Adagrah Aniakwo b, Bashiro Jimah bc, Kofi Ulzen-Appiah bc, David Hutchful a, Aida Manu a, Joyce M Ngoi a, Lily Paemka a, Yakubu Alhassan ae, Ernest Amo Obeng d, Nicole Lim f, Lisa Rajah f, Michelle Pek f…Yaw Bediako a Transl Oncol; 49: 102100, 2024 Nov, https://doi.org/10.1016/j.tranon.2024.102100 Abstract Purpose: Breast cancer is a major cause of cancer-related mortality among African women. The adoption of molecular genomic technologies in the management of cancer cases is limited in Africa. To provide much-needed insights on the feasibility and utility […]
Cellular immune response to SARS-CoV-2 and clinical presentation in individuals exposed to endemic malaria
We are pleased to share a paper from our first research collaboration with West African Centre for Cell Biology of Infectious Pathogens (WACCBIP) – University of Ghana, where we explored the link between malaria and lower COVID-19 deaths in Africa. This project is supported by Google, Bill & Melinda Gates Foundation and The Rockefeller Foundation.
Clinical disease activity in autoimmune rheumatic patients receiving COVID-19 vaccines
Our research on the COURAGE cohort of our Heritage Study has been published in BMC Rheumatology! The COvid-19 vaccine immUne Response in Autoimmune rheumatic patients: a Ghanaian Experience (COURAGE) study, led by Dr. Ida Dzifa Dey, followed 38 patients with Systemic lupus erythematous (SLE) and Rheumatoid arthritis (RA) over 12 months at Korle-Bu Teaching Hospital, to access changes in clinical disease activity following COVID-19 vaccination, and to understand vaccine immune response in this subset.
Yemaachi Furthers African Cancer Research Agenda With New Breast Cancer Mutation, Research Networks
Yemaachi Biotech is preparing to expand a whole-exome sequencing pilot study, while pushing forward several other pan-African cancer research initiatives.
Radiologic patterns of distant organ metastasis in advanced breast cancer patients
Breast cancer (BC) metastases to the abdomen and pelvis affect the liver, mesentery, retroperitoneum, peritoneum, bladder, kidney, ovary, and uterus. The study documented the radiological pattern and features of the chest, bone, abdominal and pelvic (AP) metastases among advanced breast cancer patients.
Yemaachi Presents Findings on Mutation Profiles of Ghanaian Women with Breast Cancer at AORTIC 2023; Announces Formation of African Clinical Cancer Research Network
Results presented in collaboration with Paemka Research Group at the University of Ghana represent largest sequencing study of its kind conducted entirely in Africa to date; Company’s cancer network will advance and scale precision oncology research and collaborations across the continent
BRECXOME – Whole Exome Sequencing of Breast Cancer Tumour Samples from Ghanaian Women
Yemaachi shared findings from a its BreCXome study in an abstract presentation at the 14th AORTIC International Conference on Cancer in Africa